Training Program Title

Personalized Medicine, Heterogeneity of Treatment Effect, and Implications for Comparative Effectiveness

Contributor

Tufts CTSI

CTSA Hub Administered

yes

Training Program Description

Power Point presentation relating to randomized controlled trials, registries, and observations

Competency Keywords

Clinical research, Clinical trial, Health research, Research study management

Digital Commons Disciplines

Genetics | Medical Education

Public

yes

Cost to Access

no

Competency Domains

Scientific Concepts and Research Design

Learning Objectives

This training will discuss:

-Limitations of applying the overall results of clinical trials to individual patients -Summary results of individual trials
-Explain how subgroup analyses are prone both to false-positive and false-negative results
-Approaches that might lead to more credible & actionable subgroup results
-Multidimensional risk models
-Limitations of using genetic information as a basis for exploring heterogeneity of treatment effect

Delivery Method

Combination of online and in-person

Target Learners

Principal Investigators; Clinical Research Professionals (other than PI)

Learning Level

Skilled

Frequency

On demand

Time Needed

About an hour

Associated Assessment

no

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